The nucleotide-binding domain and leucine-rich repeat related (NLR) family, pyrin domain containing 3 (NLRP3) is a multimeric protein that recognizes different PAMPs and...
Inflammation is a necessary response, and it can initiate host defense response and repair damaged tissue. However, an uncontrolled inflammatory signal can cause...
How to Boost Tight Junction Integrity Through Nutrition?
Tight Junctions (TJ) comprise different proteins that bind to the actin cytoskeleton to provide barrier integrity to our gut lining. Indeed, TJs are key assistance...
Tight Junctions: Defective Intestinal Barrier and Pathological Conditions
Our main interaction with food, pathogens, and inflammatory signals is made through our intestinal barrier. Indeed, our gut epithelium is where the absorption...
2020 changed the way many medical professionals see and assess their patients. Similar to other offices, we adapted to make sure our patients still received the...
At the current moment, we are still struggling with the COVID-19 pandemic. Even today, we are bombarded with medical information on how to prevent complications...
How Food-Induced PAMPs Influences Immune Responses in Cardiovascular Disease
The obesity pandemic has affected our population on a large scale. Indeed, this multifactorial condition is heavily influenced by numerous environmental elements...
Innate and adaptive immunity responses often take the spotlight regarding the defense and protection against pathogens. Nevertheless, barrier tissues have proven to...
Ketosis and Microbiota: Healthy Symbiosis
The link between microbiota and different factors such as exercise, genetics, disease, body composition, and nutritional intake is undeniable. However, this means...
A healthy microbiota is considered to have rich biodiversity and functions symbiotically with its host to promote wellness. However, dysbiosis is widely associated b a...