All disease starts in the gut, but how? Intestinal permeability is a great contributor to metabolic and chronic conditions, as it allows bacterial translocation. Furthermore, this triggers local and systemic inflammation. However, these two factors, combined with the presence of gut...
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It was first isolated from the Bovine Pineal gland in 1958. Nevertheless, in humans, it is the main hormone secreted by the pineal gland. Melatonin was considered a sleeping aid, and it was widely used to reduce jet-lag. Nevertheless, the chronobiological hormone has proven to have...
Gut and Intestinal Health, Nutrition and Wellness, Oxidative Stress
Western diet: Immune activation, Metainflammation and Chronic Diseases
The overweight and obesity epidemic has taken over the world, promoting the prevalence of chronic diseases. The common denominator of this problem is our sedentary lifestyle accompanied by a westernized diet. Life-style associated pathologies promote a chronic state of metabolic...
Functional Medicine, Functional Medicine Series, Health, Nutrition and Wellness, Wellness
Healthy Metals vs Toxic Metals
Metals in the body are essential for proper cellular function. That being said, in order to ensure the metals you are ingesting are good for you and what the body needs, you need to know whole sources to obtain them from and what each metal does. On the other hand, there are toxic metals...
The nucleotide-binding domain and leucine-rich repeat related (NLR) family, pyrin domain containing 3 (NLRP3) is a multimeric protein that recognizes different PAMPs and DAMPs. Furthermore, in the presence of potential danger, this inflammasome can perpetuate a potent inflammatory...
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